All Articles

• REVIEW  |  24 Oct 2021

  Roles of renin-angiotensin system in the regulation of prostate cancer bone metastasis: a critical review

  MANH TIEN TRAN. Mestastatic prostate cancer cells (MPCCs) frequently metastasize to bone, which is a “favorite soil” for colonization and proliferation of MPCCs. Prostate cancer bone mestastasis is tightly associated with tumor-induced bone lesions, most commonly caused from (1) the etiological imbalance between osteoblastic bone formation and osteoclastic bone resorption and from (2) the anti-tum...

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• REVIEW  |  19 Oct 2021

  Hereditary renal cell tumors: Clinicopathologic importance

  HARMANJOT SINGH, MUKUL K. DIVATIA, DONGHWA BAEK, JAE Y. RO. Hereditary renal cancer syndromes represent approximately 5% of renal malignancies and have distinctive clinical, histopathologic, and genetic features. Next-generation sequencing and other molecular testing methods have uncovered several hereditary renal cancer syndromes. Several autosomal dominant hereditary renal cell carcinoma (...

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• REVIEW  |  18 Oct 2021

  Squamous Cell Carcinoma of the Urinary Bladder: Clinicopathological and Molecular Update

  SUNIL VITTHALRAO JAGTOP, SWATI JAGTAP, PARNEET KAUR, SNIGDHA, VARTAK et al. Urinary bladder cancer is one of the most prevalent cancers worldwide.Squamous Cell Carcinoma (SCC) is an uncommon subtype of urinary bladder carcinoma.It is a malignant epithelial neoplasm arising in the urinary bladder demonstrating a pure squamous cell phenotype. On histopathology it is considered when tumor is showing...

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• CASE REPORT  |  18 Oct 2021

  Isolated large renal hydatid cyst treated by laparoscopic nephrectomy

  VEDA MURTHY REDDY POGULA, ERSHAD HUSSAIN GALETI, BHARGAVA REDDY KANCHIV, IFRAH AHMAD, AYESHA GALETI. Hydatid disease is caused by Echinococcus granulosus, which causes rare isolated presentation in the kidneys, and is estimated to be about 2-4% of all cases. We herein present a case of a 45-year-old symptomatic male patient with a large primary hydatid cyst in the left kidney that was treate...

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• CASE REPORT  |  18 Oct 2021

  Isolated tuberculous epididymal mass mimicking testicular malignancy: an interesting case report and lessons learnt

  TEJASWINI MANNE, SOLOMON NAZARETH, PAVITHRA VITTALRAJ et al. Tuberculous epididymal mass is a condition that presents as a painless scrotal swelling. It resembles a testicular mass and is more often diagnosed after orchidectomy. About 22% of all genitourinary tuberculosis show epididymal involvement and 22% of epididymal tuberculosis are bilateral. This report reiterates the need for an increased ...

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• REVIEW  |  31 Dec 2020

  Multilocular cystic renal neoplasm-low malignant potential (MCRN-LMP) - review

  SUNIL VITTHALRAO JAGTAP. Multilocular Cystic Renal Neoplasm of Low Malignant Potential (MCRN-LMP), previously known as multilocular cystic renal cell carcinoma as a rare variant of cystic kidney. It is composed of multiple cysts separated by thin septa covered with clear cells with no expansile growth. The termMCRN-LMPshould be used exclusively to identify a cystic kidney lesion with a small clust...

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