Annals of Urologic Oncology

All Articles

  • REVIEW  |  22 Sep 2019

    Mutations in Cancer Driver Genes: An Insight into Prostate Cancer Progression

    SAHDEO PRASAD, SANJAY K SRIVASTAVA. Prostate cancer is one of the most common uro-oncological disease in men and is globally leading cause of cancer related deaths in males. The somatic mutation has a strong link in the occurrence of cancer. Mutation in the oncogenes and tumor suppressor genes that alter key cellular functions can lead to prostate cancer initiation and progression. Whole genome se...

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  • REVIEW  |  15 Sep 2019

    Immunotherapy Landscape in Prostate Cancer: Successes, Failures and Promises

    SABEETH-UR-REHMAN BUTT, MUHAMMAD S KHAN, CARMEN MURIAS, MARIA REYES GONZALEZ-EXPOSITO et al. As research focus in oncology has recently shifted to immunomodulation, the era of introduction of immunotherapeutic agents in the management of prostate cancer has just begun. With the success of checkpoint blockade drugs in certain advanced tumours, ongoing efforts are aimed at identification and validat...

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  • REVIEW  |  02 Jul 2019

    Micropapillary Carcinoma of the Bladder: Recent Advances

    JIM HSU, JAE Y. RO. The 2016 WHO classification of tumors of the urothelial tract recently revised the classification of invasive urothelial carcinoma to include nested, microcystic, micropapillary, plasmacytoid, sarcomatoid, giant cell, and poorly differentiated variants, among others. In particular, invasive micropapillary carcinoma (IMPC) is now recognized as a distinct entity with aggressive f...

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  • CASE REPORT  |  08 May 2019

    IgG4 Related Disease of Epididymis, Mimicking Testicular Malignancy – A Rare Entity

    LEELA KRISHNA, SRIRAM KRISHNAMOORTHY, HARIHARASUDHAN SEKAR, SUSRUTHAN MURALI, et al. Immunoglobulin G4 related disease (IgG4-RD) is a systemic fibro inflammatory condition that usually presents with multiorgan involvement. We present a rare case of 54 year old male with an isolated IgG4-RD of epididymis. The patient presented with a progressive swelling of the left testicle. A clin...

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  • REVIEW  |  05 Apr 2019

    Noncoding RNAs and Its Implication as Biomarkers in Renal Cell Carcinoma: A Systematic Analysis

    SHIV VERMA, SANJAY GUPTA . Renal cell carcinoma (RCC) is one of the most devastating disease with higher mortality rates. It comprises several subtypes exhibiting distinct histological features and clinical staging. Despite recent advancement in understanding the biology of RCC success in treatment rates remains dismal. This may be partly due to lack of specific biomarkers for earl...

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  • REVIEW  |  16 Mar 2019

    Ovarian-type Tumors (Mullerian Tumors) of the Testis: Clinicopathologic Findings with Recent Advances

    MICHELLE S LIN, ALBERTO G AYALA, JAE Y RO. Ovarian-type epithelial tumors rarely occur in the human testis and paratesticular region. Histologically, these tumors closely resemble their ovarian counterparts and are therefore classified similarly to ovarian epithelial tumors. Most reported ovarian-type tumor cases are serous tumors, but the full spectrum of ovarian neoplasms has be...

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