All Articles

• RESEARCH   |  04 Nov 2019

  Trends in Primary Kidney Cancer: A South Australian Registry Review

  RICHARD HOFFMAN, ARMAN KAHOKEHR, MICHAEL O'CALLAGHAN, KATINA D'ONISE et al. Background The incidence of primary kidney cancer (PKC) has been increasing over the last three decades. This has been attributed to the liberal use of radiological examinations for unrelated indications. We investigated the incidence and survival trends of PKC in South Australia. Methods Data were provided through the So...

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• REVIEW  |  22 Sep 2019

  Mutations in Cancer Driver Genes: An Insight into Prostate Cancer Progression

  SAHDEO PRASAD, SANJAY K SRIVASTAVA. Prostate cancer is one of the most common uro-oncological disease in men and is globally leading cause of cancer related deaths in males. The somatic mutation has a strong link in the occurrence of cancer. Mutation in the oncogenes and tumor suppressor genes that alter key cellular functions can lead to prostate cancer initiation and progression. Whole genome se...

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• REVIEW  |  15 Sep 2019

  Immunotherapy Landscape in Prostate Cancer: Successes, Failures and Promises

  SABEETH-UR-REHMAN BUTT, MUHAMMAD S KHAN, CARMEN MURIAS, MARIA REYES GONZALEZ-EXPOSITO et al. As research focus in oncology has recently shifted to immunomodulation, the era of introduction of immunotherapeutic agents in the management of prostate cancer has just begun. With the success of checkpoint blockade drugs in certain advanced tumours, ongoing efforts are aimed at identification and validat...

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• REVIEW  |  02 Jul 2019

  Micropapillary Carcinoma of the Bladder: Recent Advances

  JIM HSU, JAE Y. RO. The 2016 WHO classification of tumors of the urothelial tract recently revised the classification of invasive urothelial carcinoma to include nested, microcystic, micropapillary, plasmacytoid, sarcomatoid, giant cell, and poorly differentiated variants, among others. In particular, invasive micropapillary carcinoma (IMPC) is now recognized as a distinct entity with aggressive f...

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• CASE REPORT  |  08 May 2019

  IgG4 Related Disease of Epididymis, Mimicking Testicular Malignancy – A Rare Entity

  LEELA KRISHNA, SRIRAM KRISHNAMOORTHY, HARIHARASUDHAN SEKAR, SUSRUTHAN MURALI, et al. Immunoglobulin G4 related disease (IgG4-RD) is a systemic fibro inflammatory condition that usually presents with multiorgan involvement. We present a rare case of 54 year old male with an isolated IgG4-RD of epididymis. The patient presented with a progressive swelling of the left testicle. A clin...

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• REVIEW  |  05 Apr 2019

  Noncoding RNAs and Its Implication as Biomarkers in Renal Cell Carcinoma: A Systematic Analysis

  SHIV VERMA, SANJAY GUPTA . Renal cell carcinoma (RCC) is one of the most devastating disease with higher mortality rates. It comprises several subtypes exhibiting distinct histological features and clinical staging. Despite recent advancement in understanding the biology of RCC success in treatment rates remains dismal. This may be partly due to lack of specific biomarkers for earl...

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