Table of Contents

• Diagnosis and Treatment of Adrenal Metastasis in Modern Era

  Sarah E. Matusofsky, Paris M. Fang ... Mark R. Wakefield

  The adrenal glands are a common site of metastases in many advanced stages of cancers such as lung cancer and breast cancer. Given the frequent asymptomatic nature of these adrenal metastatic tumors, patients seldom get screened for adrenal metastases unless otherwise medically indicated for. Therefore, it is essential that screening methods should be as accurate and precise as possible. In this r...

  REVIEW | Published: 11 Nov 2023

  Annals of Urologic Oncology, Volume 6 (2023), Issue 4

  Pages: 1-5   PDF(690KB)   Views：588Downloads：1

• Research Progress on the Mechanism of Androgen Receptor Signaling Pathway in Castration-Resistant Prostate Cancer

  Na Cui, Mingjie Li

  Prostate cancer (Pca) remains the most common malignancy worldwide in men, and the second leading cause of mortality only to lung cancer. Besides surgery, androgen deprivation therapy (ADT) is a major treatment for Pca. However, ADT leads to the inevitable progression of castration-resistant Pca (CRPC). The transition from hormone-dependent Pca (ADPC) to CRPC has been shown to involve reactivatio...

  REVIEW | Published: 11 Nov 2023

  Annals of Urologic Oncology, Volume 6 (2023), Issue 4

  Pages: 6-12   PDF(581KB)   Views：357Downloads：2

• Lipid Metabolism Pathway and Renal Tumor Therapy

  Wenjun Wang, Chunyan Xin

  Renal tumor remains as one of the common malignancy of the urinary system whose incidence and mortality is increasing over the years. Although the emergence of targeted drugs has greatly improved the prognosis of patients with advanced kidney cancer, the occurrence of drug resistance still brings huge treatment pressure to patients. Renal clear cell carcinoma (RCC), the most common pathological ty...

  REVIEW | Published: 31 Dec 2023

  Annals of Urologic Oncology, Volume 6 (2023), Issue 4

  Pages: 13-18   PDF(480KB)   Views：265Downloads：2

• Prediction of Metastatic Site Based On Somatic Gene Mutations in Primary Tumors in Prostate Cancer

  Paul Gomez

  Objective The goal of this research is to predict the most likely metastatic site(s) of a primary prostate cancer tumor that has been resected via radical prostatectomy; its genome has been sequenced to obtain a list of gene mutations; and after initial inspection of pelvic lymph nodes, there is no clinical evidence of metastasis. However, micrometastases might already be growing in distant organs...

  RESEARCH | Published: 24 Dec 2023

  Annals of Urologic Oncology, Volume 6 (2023), Issue 4

  Pages: 19-27   PDF(1300KB)   Views：358Downloads：0

• Diet, Physical Activity, and Smoking in Patients Living with Non-Muscle Invasive Bladder Cancer

  Elizabeth Y. Wang, Manuel Armas-Phan ... Stacey A. Kenfield

  Modifiable lifestyle factors have been implicated in bladder cancer outcomes. Further study is warranted to inform future strategies in patients with non-muscle invasive bladder cancer (NMIBC). We aim to describe modifiable behaviors (smoking, diet, and physical activity) in a cohort of patients with NMIBC....

  RESEARCH | Published: 02 Nov 2023

  Annals of Urologic Oncology, Volume 6 (2023), Issue 4

  Pages: 28-34   PDF(812KB)   Views：373Downloads：0

• Measurement of Microvessel Density Using CD105 (Endoglin) as a Marker in Prostatic Adenocarcinoma

  Sheenam Azad, Garima Sharma ... Sadaf Khan

  Introduction Angiogenesis has been proposed as a promising prognostic marker in a variety of tumours. Microvessel density (MVD) measurement is the most reliable method for the semiquantitative evaluation of angiogenesis. Endoglin (CD105) is a recognised marker of proliferating endothelium and is expressed in intra-tumoral as well as peri-tumoral vessels. It is upregulated in various cancers includ...

  RESEARCH | Published: 31 Dec 2023

  Annals of Urologic Oncology, Volume 6 (2023), Issue 4

  Pages: 35-40   PDF(484KB)   Views：244Downloads：0