Table of Contents

• Evolving Therapeutic Paradigms in Bladder Cancer: the Impact of Immunotherapy and Antibody-Drug Conjugates

  Shahd Mustafa Ibrahim, Ahmed Attia Ahmed Abdelmoaty, Ahmed Helmy Abdelhaseb

  Bladder cancer is a significant global health challenge. Despite advances in surgery and platinum-based chemotherapy over the decades, limited improvements in clinical outcomes have been observed. However, recent years have witnessed the development of immune checkpoint inhibitors (ICIs) and antibody-drug conjugates (ADCs) that has transformed the therapeutic landscape of bladder cancer across dif...

  REVIEW | Published: 24 Oct 2025

  Annals of Urologic Oncology, Articles, Online First

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• Incidentally Discovered Primary Renal Leiomyosarcoma in a Middle Aged Female Presenting with Symptoms of Incomplete Abortion: A Rare Case Report

  Rashi Maheshwari, Shikhar Chohan ... Sufian Zaheer

  Background Primary renal leiomyosarcoma (LMS) is an exceptionally rare malignant mesenchymal tumor, constituting <1.5% of all primary renal malignancies. Diagnosis is difficult because clinical and radiologic features overlap with other renal neoplasms. Case Presentation We describe a 37-year-old woman, notably younger than the typical age reported for renal LMS, who presented with abnormal uteri...

  CASE REPORT | Published: 23 Sep 2025

  Annals of Urologic Oncology, Articles, Online First

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• A Diagnostic Twist: Primary Bladder Adenocarcinoma Masquerading as an Ovarian Torsion: A Case Report on Unusual Cystic Presentation

  Sonali Kar, Neeta Verma, Suren Kumar Das

  Primary bladder adenocarcinoma (PBA) is a rare malignancy comprising of only 0.5–2% of all bladder cancers and typically presents with nonspecific urinary symptoms. Cystic presentation is extremely uncommon and can mimic other pelvic pathologies. We report a very rare case of PBA in a 40-year-old female initially diagnosed as ovarian torsion based on clinical features and ultrasound findings. Intr...

  CASE REPORT | Published: 15 Sep 2025

  Annals of Urologic Oncology, Articles, Online First

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